产品货号:
Z26236
中文名称:
SENP6抗体
英文名称:
Anti-SENP6 Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SENP6 Antibody |
指标别名 | SUMO specific peptidase 6;SSP1;SUSP1;SENP6 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,ELISA |
基因名称 | SENP6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human SENP6 recombinant protein (Position:R135-K1086). |
实际分子量 | 150KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | Sentrin-specific protease 6 is an enzyme that in humans is encoded by the SENP6 gene.It is mapped to 6q14.1.Ubiquitin-like molecules (UBLs),such as SUMO1,are structurally related to ubiquitin and can be ligated to target proteins in a similar manner as ubiquitin.However,covalent attachment of UBLs does not result in degradation of the modified proteins.SUMO1 modification is implicated in the targeting of RANGAP1 to the nuclear pore complex,as well as in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome.Like ubiquitin,UBLs are synthesized as precursor proteins,with 1 or more amino acids following the C-terminal glycine-glycine residues of the mature UBL protein.Thus,the tail sequences of the UBL precursors need to be removed by UBL-specific proteases,such as SENP6,prior to their conjugation to target proteins.SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates. |
Uniprot ID | Q9GZR1 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | SUMO specific peptidase 6 |
蛋白名全称 | Sentrin-specific protease 6 |
推荐稀释比 | Western blot(WB) 1:500~2000 (ELISA): 1:100~1000 |
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